Iron Deficiency Impacts Diastolic Function, Aerobic Exercise Capacity, and Patient Phenotyping in Heart Failure With Preserved Ejection Fraction: A Subanalysis of the OptimEx-Clin Study

AimsIron deficiency (ID) is linked to reduced aerobic exercise capacity and poor prognosis in patients with heart failure (HF) with reduced ejection fraction (HFrEF); however, data for HF with preserved ejection fraction (HFpEF) is scarce. We assessed the relationship between iron status and diastol...

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Main Authors: Andreas B. Gevaert, Stephan Mueller, Ephraim B. Winzer, André Duvinage, Caroline M. Van de Heyning, Elisabeth Pieske-Kraigher, Paul J. Beckers, Frank Edelmann, Ulrik Wisløff, Burkert Pieske, Volker Adams, Martin Halle, Emeline M. Van Craenenbroeck, for the OptimEx-Clin Study Group
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.757268/full