Post-Transplant Cyclophosphamide versus Methotrexate based Regimen as Graft Versus Host Disease prophylaxis after Allogeneic Haematopoietic Stem Cell Transplantation in patients with Acute Leukemia

Calcineurin inhibitor (CNI) and methotrexate (MTX) are used as standard GVHD prophylaxis in HSCT. Trials using High dose Post-transplant Cyclophosphamide (PT-Cy) with or without immunosuppressive agents (IS) have shown success. However, further studies are needed. To compare clinical outcomes of all...

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Bibliographic Details
Main Authors: Alaa Elshamy, Essam Abdelmohsen, Mai Denewer, Mohamed Mabed
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Hematology Reports
Online Access:https://www.pagepress.org/journals/index.php/hr/article/view/8906