PRMT3 promotes tumorigenesis by methylating and stabilizing HIF1α in colorectal cancer
Abstract Abnormal angiogenesis occurs during the growth of solid tumors resulting in increased vascular permeability to fluids and metastatic cancer cells. Anti-angiogenesis therapy for solid tumors is effective in the treatment of cancer patients. However, the efficacy of anti-angiogenesis therapy...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-11-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04352-w |