Cystic fibrosis: desensitization in delayed hypersensitivity reactions to elexacaftor/tezacaftor/ivacaftor

Cystic fibrosis: desensitization in delayed hypersensitivity reactions to elexacaftor/tezacaftor/ivacaftor

Background: Cystic fibrosis transmembrane conductance regulator modulators are the only available treatment for cystic fibrosis. Although elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is well-tolerated, rash has been reported as very frequent. In severe rashes, ELX/TEZ/IVA withdrawal is necessary,...

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Bibliographic Details
Main Authors: L. Gómez-Ganda, P. Galván-Blasco, A. Fernández-Polo, V. Cardona, B. García-Palop, CJ Parramón-Teixidó, E. Polverino, A. Álvarez-Fernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Pharmacology
Subjects:
cystic fibrosis
cystic fibrosis transmembrane conductance regulator modulator
delayed hypersensitivity
desensitization
elexacaftor/tezacaftor/ivacaftor
rash
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1392986/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1392986/full

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