Phage therapy is effective against infection by Mycobacterium ulcerans in a murine footpad model.

BACKGROUND: Buruli Ulcer (BU) is a neglected, necrotizing skin disease caused by Mycobacterium ulcerans. Currently, there is no vaccine against M. ulcerans infection. Although the World Health Organization recommends a combination of rifampicin and streptomycin for the treatment of BU, clinical mana...

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Bibliographic Details
Main Authors: Gabriela Trigo, Teresa G Martins, Alexandra G Fraga, Adhemar Longatto-Filho, António G Castro, Joana Azeredo, Jorge Pedrosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3636042?pdf=render