Designing, Constructing and Immunogenic Evaluation of Polytope DNA Constructs by the Application of Hepatitis C Virus Immunodominant Epitopes in BALB/c Mouse

Designing, Constructing and Immunogenic Evaluation of Polytope DNA Constructs by the Application of Hepatitis C Virus Immunodominant Epitopes in BALB/c Mouse

Objective: Polytope DNA vaccines, capable of focusing the cytotoxic T lymphocyte (CTL)response on critical epitopes, represent a promising approach in HCV immunotherapy. Nevertheless,due to controversial rules governing epitope processing and the low level expression/immunogenicity of recombinant po...

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Bibliographic Details
Main Authors: Arash Memarnejadian, Farzin Roohvand, Arash Arashkia, Farideh Berjisian, Mohammad Reza Aghasadeghi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2009-01-01
Series:Cell Journal
Subjects:
Epitope
Hepatitis C Virus
DNA Vaccine
Cytotoxic T-Lymphocytes
Online Access:http://celljournal.org/library/upload/article/Article4.pdf

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http://celljournal.org/library/upload/article/Article4.pdf

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