Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development

Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development

The present use of mRNA vaccines against COVID-19 has shown for the first time the potential of mRNA vaccines for infectious diseases. Here we will summarize the current knowledge about improved mRNA vaccines, i.e., the self-amplifying mRNA (saRNA) vaccines. This approach may enhance antigen express...

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Bibliographic Details
Main Authors: Christin Schmidt, Barbara S. Schnierle
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pathogens
Subjects:
vaccine
mRNA
self-amplifying RNA
alphavirus
innate immunity
Online Access:https://www.mdpi.com/2076-0817/12/1/138

Internet

https://www.mdpi.com/2076-0817/12/1/138

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