The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent

Abstract Loss of skeletal muscle mass and function occurs with increasing age. Calorie restriction (CR) increases the lifespan of C57Bl/6 mice, but not in the shorter-lived DBA/2 strain. There is some evidence that calorie restriction reduces or delays many of the age-related defects that occur in r...

Full description

Bibliographic Details
Main Authors: Luisa Boldrin, Jacob A. Ross, Charlotte Whitmore, Bruno Doreste, Charlotte Beaver, Ayad Eddaoudi, Daniel J. Pearce, Jennifer E. Morgan
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04896-y