Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain <i>Streptomyces albidoflavus</i> J1074

Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain <i>Streptomyces albidoflavus</i> J1074

<i>Streptomyces albidoflavus</i> J1074 is a popular platform to discover novel natural products via the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in improving the ability of this platform to overexpress BGCs and, consequently, enable the purific...

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Bibliographic Details
Main Authors: Borys Dolya, Olena Hryhorieva, Khrystyna Sorochynska, Maria Lopatniuk, Iryna Ostash, Vasylyna-Marta Tseduliak, Eva Baggesgaard Sterndorff, Tue Sparholt Jørgensen, Tetiana Gren, Yuriy Dacyuk, Tilmann Weber, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Microorganisms
Subjects:
<i>Streptomyces albidoflavus</i> J1074
rifampicin resistance
<i>rpoB</i>
specialized metabolites
Online Access:https://www.mdpi.com/2076-2607/11/5/1176

Internet

https://www.mdpi.com/2076-2607/11/5/1176

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