ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding

Summary: Foamy and inflammatory macrophages play pathogenic roles in metabolic disorders. However, the mechanisms that promote foamy and inflammatory macrophage phenotypes under acute-high-fat feeding (AHFF) remain elusive. Herein, we investigated the role of acyl-CoA synthetase-1 (ACSL1) in favorin...

Full description

Bibliographic Details
Main Authors: Fatema Al-Rashed, Dania Haddad, Ashraf Al Madhoun, Sardar Sindhu, Texy Jacob, Shihab Kochumon, Lina M. Obeid, Fahd Al-Mulla, Yusuf A. Hannun, Rasheed Ahmad
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Physiology
Cellular physiology
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012221

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223012221

Similar Items