Expression of a humanized viral 2A-mediated lux operon efficiently generates autonomous bioluminescence in human cells.

Expression of autonomous bioluminescence from human cells was previously reported to be impossible, suggesting that all bioluminescent-based mammalian reporter systems must therefore require application of a potentially influential chemical substrate. While this was disproven when the bacterial luci...

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Bibliographic Details
Main Authors: Tingting Xu, Steven Ripp, Gary S Sayler, Dan M Close
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4008522?pdf=render