Association of proton pump inhibitor use with survival outcomes in cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

Background: Proton pump inhibitors (PPIs) have been shown to regulate the gut microbiome and affect the response to immune checkpoint inhibitors (ICIs). Contradictory results on survival have been observed in patients concomitantly treated with ICIs and PPIs. We performed a systematic review and met...

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Bibliographic Details
Main Authors: Baoqing Chen, Chen Yang, Mihnea P. Dragomir, Dongmei Chi, Wenyan Chen, David Horst, George A. Calin, Qiaoqiao Li
Format: Article
Language:English
Published: SAGE Publishing 2022-07-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359221111703