Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

Deficiency of PKCλ/ι alleviates the liver pathologic impairment of Schistosoma japonicum infection by thwarting Th2 response

Abstract Background The activation of immune response driven by the eggs of Schistosoma japonicum and the subsequent secretions is the culprit behind granulomatous inflammation and liver fibrosis. Evidence suggests that PKCλ/ι participates in a variety of physiological and pathological processes, in...

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Bibliographic Details
Main Authors: Congjin Mei, Yingying Yang, Panpan Dong, Lijun Song, Yonghua Zhou, Yongliang Xu, Chuanxin Yu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Parasites & Vectors
Subjects:
Schistosoma japonicum
PKCλ/ι
Th2 polarization
Granuloma
Liver fibrosis
Online Access:https://doi.org/10.1186/s13071-022-05283-x

Internet

https://doi.org/10.1186/s13071-022-05283-x

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