Deviation of Trypsin Activity Using Peptide Conformational Imprints

Deviation of Trypsin Activity Using Peptide Conformational Imprints

In this study, a methodology utilizing peptide conformational imprints (PCIs) as a tool to specifically immobilize porcine pancreatic alpha-trypsin (PPT) at a targeted position is demonstrated. Owing to the fabrication of segment-mediated PCIs on the magnetic particles (PCIMPs), elegant cavities com...

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Bibliographic Details
Main Authors: Kiran Reddy Kanubaddi, Pei-Yu Huang, Ya-Lin Chang, Cheng Hsin Wu, Wei Li, Ranjith Kumar Kankala, Dar-Fu Tai, Chia-Hung Lee
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nanomaterials
Subjects:
porcine pancreatic trypsin
molecularly-imprinted polymers
magnetic particles
conformational imprint
secondary structure
Online Access:https://www.mdpi.com/2079-4991/11/2/334

Internet

https://www.mdpi.com/2079-4991/11/2/334

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