UBE2T promotes stage I lung adenocarcinoma progression through PBX1 ubiquitination and PBX1/RORA regulation

UBE2T promotes stage I lung adenocarcinoma progression through PBX1 ubiquitination and PBX1/RORA regulation

Abstract Background Post-translational modification pathway of protein ubiquitination is intricately associated with tumorigenesis. We previously reported elevated ubiquitin-conjugating enzyme 2T (UBE2T) as an independent risk factor in stage I lung adenocarcinoma and promoting cellular proliferatio...

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Bibliographic Details
Main Authors: Yujie Deng, Xiaohui Chen, Xuzheng Chen, Chuanzhong Huang, Zhiguang Zhang, Zhenguo Xu, Xiurong Wang, Jiamin Wu, Li Li, Jun Song, Ruixiang Zhou
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Cancer
Subjects:
Ubiquitination modification
UBE2T
RORA
Progression
Lung adenocarcinoma
Online Access:https://doi.org/10.1186/s12885-024-12887-2

Internet

https://doi.org/10.1186/s12885-024-12887-2

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