The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC ActivationSummary

The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC ActivationSummary

Background & Aims: Transforming growth factor-β1 (TGF-β1) plays important roles in chronic liver diseases, including metabolic dysfunction–associated steatotic liver disease (MASLD). MASLD involves various biological processes including dysfunctional cholesterol metabolism and contributes to...

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Bibliographic Details
Main Authors: Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, Ye Yao, Seddik Hammad, Anne Dropmann, Marinela Krizanac, Claudia Rubie, Laura Kim Feiner, Matthias Glanemann, Matthias P.A. Ebert, Ralf Weiskirchen, Yoav I. Henis, Marcelo Ehrlich, Steven Dooley
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Cholesterol Metabolism
TGF-β1
Hepatic Fibrosis
MASLD
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2300228X

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http://www.sciencedirect.com/science/article/pii/S2352345X2300228X

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