The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps

The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps

Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses and epithelial barrier, mucociliary, and olfactory dysfunction. The inflammatory cytokines interleukin (IL)-4, IL-13, and IL-5 are key mediators driving and per...

Full description

Bibliographic Details
Main Authors: Claus Bachert, Alexandra Hicks, Simon Gane, Anju T. Peters, Philippe Gevaert, Scott Nash, Julie E. Horowitz, Harry Sacks, Juby A. Jacob-Nara
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
chronic rhinosinusitis with nasal polyps
CRSwNP
type 2 inflammation
cytokine
interleukin-4
interleukin-13
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356298/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356298/full

Similar Items