The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps

The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps

Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses and epithelial barrier, mucociliary, and olfactory dysfunction. The inflammatory cytokines interleukin (IL)-4, IL-13, and IL-5 are key mediators driving and per...

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Bibliographic Details
Main Authors:	Claus Bachert, Alexandra Hicks, Simon Gane, Anju T. Peters, Philippe Gevaert, Scott Nash, Julie E. Horowitz, Harry Sacks, Juby A. Jacob-Nara
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Immunology
Subjects:	chronic rhinosinusitis with nasal polyps CRSwNP type 2 inflammation cytokine interleukin-4 interleukin-13
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356298/full

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