A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis

A genome-wide association study of neutrophil count in individuals associated to an African continental ancestry group facilitates studies of malaria pathogenesis

Abstract Background 'Benign ethnic neutropenia' (BEN) is a heritable condition characterized by lower neutrophil counts, predominantly observed in individuals of African ancestry, and the genetic basis of BEN remains a subject of extensive research. In this study, we aimed to dissect the g...

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Bibliographic Details
Main Authors: Andrei-Emil Constantinescu, David A. Hughes, Caroline J. Bull, Kathryn Fleming, Ruth E. Mitchell, Jie Zheng, Siddhartha Kar, Nicholas J. Timpson, Borko Amulic, Emma E. Vincent
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Human Genomics
Subjects:
Malaria
Neutrophil count
Mendelian randomization
GWAS
African ancestry
Online Access:https://doi.org/10.1186/s40246-024-00585-w

Internet

https://doi.org/10.1186/s40246-024-00585-w

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