Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial

Abstract Background Many critically ill children face long-term developmental impairments. The PEPaNIC trial attributed part of the problems at the level of neurocognitive and emotional/behavioral development to early use of parenteral nutrition (early-PN) in the PICU, as compared with withholding i...

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Main Authors: Ilse Vanhorebeek, An Jacobs, Liese Mebis, Karolijn Dulfer, Renate Eveleens, Hanna Van Cleemput, Pieter J. Wouters, Ines Verlinden, Koen Joosten, Sascha Verbruggen, Greet Van den Berghe
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-022-04010-3