Therapeutic advances of targeting receptor tyrosine kinases in cancer

Therapeutic advances of targeting receptor tyrosine kinases in cancer

Abstract Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained significant clinical attention in oncology due to their central role in cancer pathogenesis. Genetic alterations, including mutations, amplifications, and overexpression of certain RTKs, are critical in cre...

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Bibliographic Details
Main Authors: Ciprian Tomuleasa, Adrian-Bogdan Tigu, Raluca Munteanu, Cristian-Silviu Moldovan, David Kegyes, Anca Onaciu, Diana Gulei, Gabriel Ghiaur, Hermann Einsele, Carlo M. Croce
Format: Article
Language:English
Published: Nature Publishing Group 2024-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-01899-w

Internet

https://doi.org/10.1038/s41392-024-01899-w

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