Zebrafish duox mutations provide a model for human congenital hypothyroidism
Thyroid dyshormonogenesis is a leading cause of congenital hypothyroidism, a highly prevalent but treatable condition. Thyroid hormone (TH) synthesis is dependent on the formation of reactive oxygen species (ROS). In humans, the primary sources for ROS production during thyroid hormone synthesis are...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-02-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/2/bio037655 |