Zebrafish duox mutations provide a model for human congenital hypothyroidism

Thyroid dyshormonogenesis is a leading cause of congenital hypothyroidism, a highly prevalent but treatable condition. Thyroid hormone (TH) synthesis is dependent on the formation of reactive oxygen species (ROS). In humans, the primary sources for ROS production during thyroid hormone synthesis are...

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Bibliographic Details
Main Authors: Kunal Chopra, Shoko Ishibashi, Enrique Amaya
Format: Article
Language:English
Published: The Company of Biologists 2019-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/2/bio037655