Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury

Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury

Renal fibrosis is a common process of various kidney diseases. Autophagy is an important cell biology process to maintain cellular homeostasis. In addition, autophagy is involved in the pathogenesis of various renal disease, including acute kidney injury, glomerular diseases, and renal fibrosis. How...

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Bibliographic Details
Main Authors: Hyun Jin Jung, Hyun-Jin An, Mi-Gyeong Gwon, Hyemin Gu, Seongjae Bae, Sun-Jae Lee, Young-Ah Kim, Jaechan Leem, Kwan-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
renal fibrosis
autophagy
oligodeoxynucleotide
decoy
antisense
mTOR
Online Access:https://www.mdpi.com/1420-3049/27/3/766

Internet

https://www.mdpi.com/1420-3049/27/3/766

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