<i>Per1/Per2</i> knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis

<i>Per1/Per2</i> knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis

Disturbances in circadian rhythms are known to affect immune functions. However, the long-term impact of abnormal circadian rhythms on the immune-related functions of the spleen are poorly understood. Hence, we aimed to investigate the immune-related functions of spleen in <i>Per1/Per2</i&g...

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Bibliographic Details
Main Authors: Ruyi He, Shijie Zhang, Jiale Yu, Xiaojie Yu, Jian Wang, Yi Qiu, Wenting Zhou, Fangyi Wang, Feng Ren, Zhiguo Liu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
circadian clock
<i>Per1/Per2</i>
spleen lymphocytes
ferroptosis
Online Access:https://www.mdpi.com/1422-0067/23/21/12962

Internet

https://www.mdpi.com/1422-0067/23/21/12962

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