Chronic lithium administration in a mouse model for Krabbe disease

Chronic lithium administration in a mouse model for Krabbe disease

Abstract Krabbe disease (KD; or globoid cell leukodystrophy) is an autosomal recessive lysosomal storage disorder caused by deficiency of the galactosylceramidase (GALC) enzyme. No cure is currently available for KD. Clinical applied treatments are supportive only. Recently, we demonstrated that two...

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Bibliographic Details
Main Authors: Ambra Del Grosso, Gabriele Parlanti, Lucia Angella, Nadia Giordano, Ilaria Tonazzini, Elisa Ottalagana, Sara Carpi, Roberto Maria Pellegrino, Husam B. R. Alabed, Carla Emiliani, Matteo Caleo, Marco Cecchini
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:JIMD Reports
Subjects:
autophagy
globoid cell leukodystrophy
Krabbe
lithium
psychosine
Twitcher
Online Access:https://doi.org/10.1002/jmd2.12258

Internet

https://doi.org/10.1002/jmd2.12258

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