Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness.

Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness.

Although articular cartilage degeneration represents a major public health problem, the underlying molecular mechanisms are still poorly characterized. We have previously utilized genome-wide expression analysis to identify specific markers of porcine articular cartilage, one of them being Thrombosp...

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Bibliographic Details
Main Authors: Anke Jeschke, Martin Bonitz, Maciej Simon, Stephanie Peters, Wolfgang Baum, Georg Schett, Wolfgang Ruether, Andreas Niemeier, Thorsten Schinke, Michael Amling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667928?pdf=render

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http://europepmc.org/articles/PMC4667928?pdf=render

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