Pharmacological Characterization of Veldoreotide as a Somatostatin Receptor 4 Agonist

Veldoreotide, a somatostatin analogue, binds to the somatostatin receptors (SSTR) 2, 4, and 5. The current aim was to assess its pharmacological activity as an SSTR4 agonist. G-protein signaling was assessed using a fluorescence-based membrane potential assay in human embryonic kidney 293 (HEK293) c...

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Bibliographic Details
Main Authors: Pooja Dasgupta, Thomas Gűnther, Stefan Schulz
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/10/1075