Spatiotemporally controlled, aptamers-mediated growth factor release locally manipulates microvasculature formation within engineered tissues

Spatiotemporally controlled, aptamers-mediated growth factor release locally manipulates microvasculature formation within engineered tissues

Spatiotemporally controlled growth factor (GF) delivery is crucial for achieving functional vasculature within engineered tissues. However, conventional GF delivery systems show inability to recapitulate the dynamic and heterogeneous nature of developing tissue's biochemical microenvironment. H...

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Bibliographic Details
Main Authors: Deepti Rana, Ajoy Kandar, Nasim Salehi-Nik, Ilyas Inci, Bart Koopman, Jeroen Rouwkema
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-06-01
Series:Bioactive Materials
Subjects:
Aptamers
Vascular endothelial growth factor
Spatiotemporal release
Co-culture
Vascularization
Biomaterials
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21004862

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X21004862

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