Nanospermidine in Combination with Nanofenretinide Induces Cell Death in Neuroblastoma Cell Lines

Nanospermidine in Combination with Nanofenretinide Induces Cell Death in Neuroblastoma Cell Lines

A new strategy to cause cell death in tumors might be the increase of intracellular polyamines at concentrations above their physiological values to trigger the production of oxidation metabolites at levels exceeding cell tolerance. To test this hypothesis, we prepared nanospermidine as a carrier fo...

Full description

Bibliographic Details
Main Authors: Pietro Lodeserto, Martina Rossi, Paolo Blasi, Giovanna Farruggia, Isabella Orienti
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
intracellular polyamine levels
ROS increase
NLF
BR6
antitumor activity
cell motility
Online Access:https://www.mdpi.com/1999-4923/14/6/1215

Internet

https://www.mdpi.com/1999-4923/14/6/1215

Similar Items