The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ

<p>Abstract</p> <p>Backgrounds</p> <p>Increasing evidence shows that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) possesses potent anti-inflammatory and immunomodulatory properties. It is tempting to evaluate the potential of SAHA as a therap...

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Bibliographic Details
Main Authors: Hashioka Sadayuki, Klegeris Andis, McGeer Patrick L
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/113