UGRP1-modulated MARCO+ alveolar macrophages contribute to age-related lung fibrosis
Abstract The aging lungs are vulnerable to chronic pulmonary diseases; however, the underlying mechanisms are not well understood. In this study, we compared the aging lungs of 20–24-month-old mice with the young of 10–16-week-old mice, and found that aging airway epithelial cells significantly upre...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-023-00338-8 |