UGRP1-modulated MARCO+ alveolar macrophages contribute to age-related lung fibrosis

Abstract The aging lungs are vulnerable to chronic pulmonary diseases; however, the underlying mechanisms are not well understood. In this study, we compared the aging lungs of 20–24-month-old mice with the young of 10–16-week-old mice, and found that aging airway epithelial cells significantly upre...

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Bibliographic Details
Main Authors: Yongyan Chen, Xiaolei Hao, Ming Li, Zhigang Tian, Min Cheng
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-023-00338-8