The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation
Reformulating poorly water-soluble drugs as supersaturated lipid-based formulations achieves higher drug loading and potentially improves solubilisation and bioavailability. However, for the weak base blonanserin, silica solidified supersaturated lipid-based formulations have demonstrated reduced in...
Main Authors: | , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
MDPI AG
2023-01-01
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丛编: | Pharmaceutics |
主题: | |
在线阅读: | https://www.mdpi.com/1999-4923/15/1/284 |