Neopentyl glycol-based radiohalogen-labeled amino acid derivatives for cancer radiotheranostics

Neopentyl glycol-based radiohalogen-labeled amino acid derivatives for cancer radiotheranostics

Abstract Background L-type amino acid transporter 1 (LAT1) is overexpressed in various cancers; therefore, radiohalogen-labeled amino acid derivatives targeting LAT1 have emerged as promising candidates for cancer radiotheranostics. However, 211At-labeled amino acid derivatives exhibit instability a...

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Bibliographic Details
Main Authors: Yuta Kaizuka, Hiroyuki Suzuki, Tadashi Watabe, Kazuhiro Ooe, Atsushi Toyoshima, Kazuhiro Takahashi, Koichi Sawada, Takashi Iimori, Yoshitada Masuda, Takashi Uno, Kento Kannaka, Tomoya Uehara
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Astatine-211
Theranostics
Neopentyl
Radiohalogen
Amino acid
Online Access:https://doi.org/10.1186/s41181-024-00244-4

Internet

https://doi.org/10.1186/s41181-024-00244-4

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