Effects of Eltrombopag on In Vitro Macrophage Polarization in Pediatric Immune Thrombocytopenia

Effects of Eltrombopag on In Vitro Macrophage Polarization in Pediatric Immune Thrombocytopenia

Immune Thrombocytopenia (ITP) is an autoimmune disease characterized by autoantibodies-mediated platelet destruction, a prevalence of M1 pro-inflammatory macrophage phenotype and an elevated T helper 1 and T helper 2 lymphocytes (Th1/Th2) ratio, resulting in impairment of inflammatory profile and im...

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Bibliographic Details
Main Authors: Alessandra Di Paola, Giuseppe Palumbo, Pietro Merli, Maura Argenziano, Chiara Tortora, Luisa Strocchio, Domenico Roberti, Claudia Santoro, Silverio Perrotta, Francesca Rossi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
immune thrombocytopenia
eltrombopag
macrophages
M1
M2
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/1/97

Internet

https://www.mdpi.com/1422-0067/22/1/97

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