Improved synthesis of 6-bromo-7-[11C]methylpurine for clinical use

Improved synthesis of 6-bromo-7-[11C]methylpurine for clinical use

Abstract Background Multidrug resistance-associated protein 1 (MRP1), an energy-dependent efflux pump, is expressed widely in various tissues and contributes to many physiological and pathophysiological processes. 6-Bromo-7-[11C]methylpurine ([11C]7m6BP) is expected to be useful for the assessment o...

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Bibliographic Details
Main Authors: Toshimitsu Okamura, Tatsuya Kikuchi, Masanao Ogawa, Ming-Rong Zhang
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
6-Bromopurine
Carbon-11
Methylation
MRP1
Regioselectivity
Online Access:https://doi.org/10.1186/s41181-024-00240-8

Internet

https://doi.org/10.1186/s41181-024-00240-8

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