Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis

Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis

Abstract Background Acute lymphoblastic leukemia is an aggressive neoplasm and seriously threatens human health. A14 is one kind of semisynthetic aurone that exhibits the capability to inhibit prostate cancer, but little is known about the role of A14 on T-cell acute lymphoblastic leukemia. Methods...

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Bibliographic Details
Main Authors: Meng Wang, Lisi Li, Tengyun Fan, Lixue Cao, Jiayi Zhang, Shuang Li, Chunming Liu, Xifu Liu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Chinese Medicine
Subjects:
Semisynthetic aurones A14
T-cell acute lymphoblastic leukemia
Cell proliferation
Cell cycle
Apoptosis
Online Access:https://doi.org/10.1186/s13020-022-00693-6

Internet

https://doi.org/10.1186/s13020-022-00693-6

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