Store-Operated Calcium Channels as Drug Target in Gastroesophageal Cancers

Store-Operated Calcium Channels as Drug Target in Gastroesophageal Cancers

Gastroesophageal cancers, including tumors occurring in esophagus and stomach, usually have poor prognosis and lack effective chemotherapeutic drugs for treatment. The association between dysregulated store-operated calcium entry (SOCE), a key intracellular Ca2+ signaling pathway and gastroesophagea...

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Bibliographic Details
Main Authors: Yan Chang, Souvik Roy, Zui Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
orai
esophageal squamous cell carcinoma
drug resistance
cancer stem cells
calcium signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.668730/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.668730/full

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