Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications

Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications

Abstract Hypoxia is a remarkable trait of the tumor microenvironment (TME). When facing selective pressure, tumor cells show various adaptive characteristics, such as changes in the expression of cancer hallmarks (increased proliferation, suppressed apoptosis, immune evasion, and so on) and more fre...

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Bibliographic Details
Main Authors: Guangpeng He, Xueqiang Peng, Shibo Wei, Shuo Yang, Xinyu Li, Mingyao Huang, Shilei Tang, Hongyuan Jin, Jiaxing Liu, Sheng Zhang, Hongyu Zheng, Qing Fan, Jingang Liu, Liang Yang, Hangyu Li
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-021-01440-5

Internet

https://doi.org/10.1186/s12943-021-01440-5

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