A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status

A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status

Abstract Background Recurrence of drug-resistant tuberculosis (DR-TB) after treatment occurs through relapse of the initial infection or reinfection by a new drug-resistant strain. Outbreaks of DR-TB in high burden regions present unique challenges in determining recurrence status for effective dise...

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Bibliographic Details
Main Authors: Kurt Wollenberg, Michael Harris, Andrei Gabrielian, Nelly Ciobanu, Dumitru Chesov, Alyssa Long, Jessica Taaffe, Darrell Hurt, Alex Rosenthal, Michael Tartakovsky, Valeriu Crudu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium tuberculosis
Recurrent infection
Multi-drug resistant
Extensively-drug resistant
Moldova
Online Access:https://doi.org/10.1186/s12879-019-4739-z

Internet

https://doi.org/10.1186/s12879-019-4739-z

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