Single-Cell RNA Sequencing of Human Corpus Cavernosum Reveals Cellular Heterogeneity Landscapes in Erectile Dysfunction

Single-Cell RNA Sequencing of Human Corpus Cavernosum Reveals Cellular Heterogeneity Landscapes in Erectile Dysfunction

PurposeTo assess the diverse cell populations of human corpus cavernosum in patients with severe erectile dysfunction (ED) at the single-cell level.MethodsPenile tissues collected from three patients were subjected to single-cell RNA sequencing using the BD Rhapsody™ platform. Common bioinformatics...

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Bibliographic Details
Main Authors: Dong Fang, Xiao-Hui Tan, Wen-Peng Song, Yang-Yang Gu, Jian-Cheng Pan, Xiao-Qing Yang, Wei-Dong Song, Yi-Ming Yuan, Jing Peng, Zhi-Chao Zhang, Zhong-Cheng Xin, Xue-Song Li, Rui-Li Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Endocrinology
Subjects:
endothelial cells
erectile dysfunction
fibroblasts
RNA-seq
smooth muscle cells
single-cell analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.874915/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.874915/full

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