The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

The control of self-renewal and differentiation of neural stem and progenitor cells is a crucial issue in stem cell and cancer biology. Drosophila type II neuroblast lineages are prone to developing impaired neuroblast homeostasis if the limited self-renewing potential of intermediate neural progeni...

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Bibliographic Details
Main Authors: Chwee Tat Koe, Song Li, Fabrizio Rossi, Jack Jing Lin Wong, Yan Wang, Zhizhuo Zhang, Keng Chen, Sherry Shiying Aw, Helena E Richardson, Paul Robson, Wing-Kin Sung, Fengwei Yu, Cayetano Gonzalez, Hongyan Wang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-03-01
Series:eLife
Subjects:
neuroblast
self-renewal
differentiation
dedifferentiation
intermediate neural progenitor
Drosophila
Online Access:https://elifesciences.org/articles/01906

Internet

https://elifesciences.org/articles/01906

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