Hypertensive disorders of pregnancy share common cfDNA methylation profiles

Abstract Hypertensive disorders of pregnancy (HDP) contribute substantially to perinatal morbidity and mortality. Epigenetic changes point towards cardio-metabolic dysregulation for these vascular disorders. In early pregnancy, epigenetic changes using cell free DNA (cfDNA) are largely unexplored. W...

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Bibliographic Details
Main Authors: Marialuigia Spinelli, Jarmila A. Zdanowicz, Irene Keller, Pamela Nicholson, Luigi Raio, Sofia Amylidi-Mohr, Beatrice Mosimann, Daniel Surbek, Martin Mueller
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24348-6