CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer

CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer

Summary: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. The tumor microenvironment (TME) plays a major regulatory role in TNBC progression and is highly infiltrated by suppressive immune cells that reduce anti-tumor immune activity. Although regulatory B cells (Br...

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Bibliographic Details
Main Authors: Stav Rabani, Emine Gulsen Gunes, Martin Gunes, Bianca Pellegrino, Bar Lampert, Keren David, Raju Pillai, Aimin Li, Shirly Becker-Herman, Steven T. Rosen, Idit Shachar
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724012713

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http://www.sciencedirect.com/science/article/pii/S2211124724012713

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