NF90–NF45 is essential for β cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway

Abstract The Nuclear Factor 90 (NF90)–NF45 complex has been known to regulate the progression of transcription, mRNA stability, translational inhibition, RNA export and microRNA biogenesis. However, the physiological functions of the NF90–NF45 complex remain unclear. We newly discovered that the NF9...

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Bibliographic Details
Main Authors: Sylvia Lai, Takuma Higuchi, Masayuki Tsuda, Yasunori Sugiyama, Keiko Morisawa, Taketoshi Taniguchi, Shuji Sakamoto
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12600-y