SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images

SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images

Abstract Background Drug occupancy studies with positron emission tomography imaging are used routinely in early phase drug development trials. Recently, our group introduced the Lassen Plot Filter, an extended version of the standard Lassen plot to estimate voxel-level occupancy images. Occupancy i...

Full description

Bibliographic Details
Main Authors: Alaaddin Ibrahimy, Jocelyn Hoye, Hao Wu, Bart de Laat, Su Jin Kim, David L. Wilson, Evan D. Morris
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:EJNMMI Physics
Subjects:
Drug occupancy
Brain imaging
PET simulation
EC50 images
Functional clustering
Accuracy and precision
Online Access:https://doi.org/10.1186/s40658-023-00600-4

Internet

https://doi.org/10.1186/s40658-023-00600-4

Similar Items