Enhanced Anticancer Efficacy of Dual Drug-Loaded Self-Assembled Nanostructured Lipid Carriers Mediated by pH-Responsive Folic Acid and Human-Derived Cell Penetrating Peptide dNP2

Enhanced Anticancer Efficacy of Dual Drug-Loaded Self-Assembled Nanostructured Lipid Carriers Mediated by pH-Responsive Folic Acid and Human-Derived Cell Penetrating Peptide dNP2

The poor ability of recognition and penetration of chemotherapeutic agents to tumor cells are still great challenges for targeted breast cancer treatment. Herein, we established a tumor-targeted nanostructured lipid carrier encapsulating gambogic acid (GA) and paclitaxel (PTX), which was co-modified...

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Bibliographic Details
Main Authors: Zhe Ma, Jiaxin Pi, Ying Zhang, Huan Qin, Bing Zhang, Nan Li, Zheng Li, Zhidong Liu
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
breast cancer
gambogic acid
paclitaxel
cell penetrating peptide
pH sensitive folic acid
Online Access:https://www.mdpi.com/1999-4923/13/5/600

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https://www.mdpi.com/1999-4923/13/5/600

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