<i>N</i>-Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization

Leveraging the T cell immunity against tumors represents a revolutionary type of cancer therapy. 4-1BB is a well-characterized costimulatory immune receptor existing on activated T cells and mediating their proliferation and cytotoxicity under infectious diseases and cancers. Despite the accumulatin...

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Bibliographic Details
Main Authors: Ruoxuan Sun, Alyssa Min Jung Kim, Allison A. Murray, Seung-Oe Lim
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/1/162