Endothelium Activation during Severe Yellow Fever Triggers an Intense Cytokine-Mediated Inflammatory Response in the Liver Parenchyma

Yellow fever (YF) is a pansystemic disease caused by the yellow fever virus (YFV), the prototype species of the family <i>Flaviviridae</i> and genus <i>Flavivirus</i>, and has a highly complex host-pathogen relationship, in which endothelial dysfunction reflects viral disease...

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Main Authors: Fábio Alves Olímpio, Luiz Fábio Magno Falcão, Marcos Luiz Gaia Carvalho, Jeferson da Costa Lopes, Caio Cesar Henriques Mendes, Arnaldo Jorge Martins Filho, Carlos Augusto Moreira da Silva, Vanessa do Socorro Cabral Miranda, Lais Carneiro dos Santos, Fellipe Souza da Silva Vilacoert, Ana Cecília Ribeiro Cruz, Vanessa Costa Alves Galúcio, Raimunda do Socorro da Silva Azevedo, Lívia Caricio Martins, Maria Irma Seixas Duarte, Jorge Rodrigues de Sousa, Pedro Fernando da Costa Vasconcelos, Juarez Antônio Simões Quaresma
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/1/101