H2O2 INDUCES APOPTOSIS OF RABBIT CHONDROCYTES VIA BOTH THE EXTRINSIC AND THE CASPASE-INDEPENDENT INTRINSIC PATHWAYS

Osteoarthritis (OA), one of the most common joint diseases with unknown etiology, is characterized by the progressive destruction of articular cartilage and the apoptosis of chondrocytes. The purpose of this study is to elucidate the molecular mechanisms of H2O2-mediated rabbit chondrocytes apoptosi...

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Bibliographic Details
Main Authors: CAIPING ZHUANG, XIAOPING WANG, TONGSHENG CHEN
Format: Article
Language:English
Published: World Scientific Publishing 2013-07-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545813500223