FOXN1: a master regulator gene of thymic epithelial development programme

FOXN1: a master regulator gene of thymic epithelial development programme

T cell ontogeny is a sophisticated process, which takes place within the thymus through a series of well-defined discrete stages. The process requires a proper lympho-stromal interaction. In particular, cortical and medullary thymic epithelial cells (cTECs, mTECs) drive T cell differentiation, educa...

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Bibliographic Details
Main Authors: Rosa eRomano, Loredana ePalamaro, Anna eFusco, Giuliana eGiardino, Vera eGallo, Luigi eDel Vecchio, Claudio ePignata
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Thymus Gland
FoxN1 gene
TECs
Immunedeficiency
Nude SCID
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00187/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00187/full

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